![]() ![]() In contrast, where in the brain and how exactly values are compared to make a decision remains an open question. Recent work demonstrated that offer values encoded in OFC are causal to choices 1. This result implies that neuronal populations in OFC participate in value comparison. Here we show that weak electrical stimulation of OFC specifically disrupts value comparison without altering offer values. Conversely, the hypothesis that OFC contributes to value comparison has not been confirmed. Recent work demonstrates that choices are causally linked to the activity of offer value cells. The encoded variables capture both the input (offer value) and the output (chosen juice, chosen value) of the decision process, suggesting that values are compared within OFC. Three groups of neurons were identified: offer value cells encoding the value of individual offers, chosen juice cells encoding the identity of the chosen juice, and chosen value cells encoding the value of the chosen offer. Previous studies examined neuronal activity in the orbitofrontal cortex (OFC) of monkeys choosing between different types of juices. Economic choices between goods entail the computation and comparison of subjective values.
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